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ONGOING GRANTS

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  1. PhaseI/II Clinical trial of a novel asparaginase mutant for the treatment of primary and relapse acute lymphatic leukemia. Early Translational Accelerator grant, BIRAC, DBT, Govt. of India (2021-2023)

  2. E. coli L-asparaginase variant for the treatment of acute lymphoblastic leukemia, SERB-TETRA (2023-25) 

  3. Reversing antimicrobial resistance (AMR), INTPART-International Network Project, Funded by Research Council of Norway, Norway (2020-23).

  4. Chemical modifications of novel asparaginase variants to improve the treatment of primary and relapse childhood acute lymphatic leukemia. SERB, Department of Science and Technology,  Govt. of India (2020-2023)

  5. Developement of theranostic targeted magnetic nanoparticles for diagnostics and treatment of tuberculosis. Department of Science and Technology, Govt. of India and Russian Foundation (DST-RFBR), Indo-Russian joint research grant (2020-2023)

  6. Integrative approach for genomic analysis and drug repurposing of MDR/XDR TB from Northeastern India for better disease interventions. Department of Biotechnology, Govt. of India

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COMPLETED GRANTS

  1. Development of Novel Benzo Fused Heterocycles to Improve the Treatment of Drug Resistant Tuberculosis. DBT, Govt. of India (2021-22)

  2. Pharmacological evaluation of a novel asparaginase used for the treatment of  childhood ALL. Board of Research in Nuclear Sciences (BRNS), DAE, Govt. of  India (2018-2021)

  3. To study the role of mesenchymal stem cells in the pathogenesis of tuberculosis in bone marrow. Department of Biotechnology, Govt. of India (2017-2022)

  4. Evaluation of antileukemic and immunogenicity properties of engineered Escherichia coli asparaginase-II for the treatment of acute lymphoblastic leukemia in preclinical model.  Department of Science and Technology, Govt. of India (2015-2018)

  5. Development of novel asparaginase based therapy for the treatment of acute lymphatic leukemia. BIG, BIRAC, Department of Biotechnology, Govt. of India (2017-2018)

  6. Identification and testing of cationic antimicrobial peptides from human granulocytes    against mycobacteria: an implication on polypeptide based therapy for the treatment of tuberculosis. Department of Biotechnology, Govt. of India (2013-2016)

  7. Delivery of Drug-encapsulating Nanoparticles to Macrophages and their Role in the   Induction of Innate and Adaptive Immune Responses for the Treatment of  tuberculosis. Department of Science and Technology, Govt. of India (2013-2016)

  8. Identification and elucidation of role of glycoproteins in the pathogenesis of  Mycobacterium  tuberculosis: a study on the implications of mycobacteria glycoproteins in the modulation of host immune responses and drug targets. Indian   Council of Medical Research, Govt. of India (2012-2015)

  9. Nanobead based novel strategies for the efficient delivery of drug molecules for the  treatment of tuberculosis. Department of Biotechnology, Govt. of India (2010-2014)

  10. Improving the properties of L-asparaginase used for the treatment of acute lymphatic leukemia. Department of Science and Technology, Govt. of India (2010-2013)

  11. Construction of Mycobacterium tuberculosis Glmu mutants by site directed mutagenesis, Open Source Drug Delivery (OSDD), CSIR, Govt. of India, 2010

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